INDUCTION OF COVALENTLY CROSSLINKED P62 OLIGOMERS WITH REDUCED BINDING TO POLYUBIQUITINATED PROTEINS BY THE AUTOPHAGY INHIBITOR VERTEPORFIN.

Autophagy is a cellular catabolic process responsible for the degradation of cytoplasmic constituents, including organelles and long-lived proteins, that helps maintain cellular homeostasis and protect against various cellular stresses.Verteporfin is a benzoporphyrin derivative used clinically in photodynamic therapy to treat macular degeneration.V

The quality and safety of food products is one of the main priorities of the Russian State policy in the field of nutrition and well-being of the population.Grape wines are a special type of food product; they are alcoholic beverages obtained as a result of complete or incomplete fermentation of whole or crushed fresh grapes or grape must.The combi